If the road sign Stop is posted before a junction, you must stop completely and give way before proceeding. This applies regardless of whether there is any traffic on the intersecting road or not. The rules are designed in this way to ensure that drivers who have a duty to stop really do so and check traffic both ways before proceeding.
When you have a duty to stop, you should do so at the stop line or, if there is no line, just before, but not on, the intersecting road – where you can be clearly seen and have a clear view. You may only proceed when you can do so without endangering or obstructing other road users.